Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-3-1
pubmed:abstractText
Medullary and papillary thyroid carcinomas are often associated with oncogenic activation of the RET tyrosine kinase. We evaluated whether the biaryl urea BAY 43-9006, which is known to inhibit several other tyrosine kinases, blocks RET kinase function and oncogenic activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1460-2105
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
326-34
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:16507829-Administration, Oral, pubmed-meshheading:16507829-Animals, pubmed-meshheading:16507829-Antineoplastic Agents, pubmed-meshheading:16507829-Benzenesulfonates, pubmed-meshheading:16507829-Cell Cycle, pubmed-meshheading:16507829-Drug Administration Schedule, pubmed-meshheading:16507829-Enzyme Inhibitors, pubmed-meshheading:16507829-Fibroblasts, pubmed-meshheading:16507829-Immunoblotting, pubmed-meshheading:16507829-Inhibitory Concentration 50, pubmed-meshheading:16507829-Mice, pubmed-meshheading:16507829-Mice, Nude, pubmed-meshheading:16507829-Mutation, pubmed-meshheading:16507829-NIH 3T3 Cells, pubmed-meshheading:16507829-Phosphorylation, pubmed-meshheading:16507829-Phosphotransferases, pubmed-meshheading:16507829-Proto-Oncogene Proteins c-ret, pubmed-meshheading:16507829-Pyridines, pubmed-meshheading:16507829-Thyroid Neoplasms, pubmed-meshheading:16507829-Transfection, pubmed-meshheading:16507829-Transplantation, Heterologous
pubmed:year
2006
pubmed:articleTitle
BAY 43-9006 inhibition of oncogenic RET mutants.
pubmed:affiliation
Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II, Naples, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't