Linked Life Data

16453365

Source:http://linkedlifedata.com/resource/pubmed/id/16453365

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2006-3-8
pubmed:abstractText
Facially amphiphilic (FA) phenylene ethynylene (PE) polymers that self-assemble in aqueous solution were studied by small-angle X-ray diffraction (SAXD) and found to self-assemble into bilayers with a fully extended backbone. The resulting bilayers have long-range liquid-crystalline order. This self-assembly is programmed into the molecule by placing polar and nonpolar groups at precise locations so that they segregate onto opposite sides of the molecular structure. The absence of FA patterning generated an amorphous sample confirming the importance of this programmed amphiphilicity in the self-assembly process. Facially amphiphilic patterning represents a new design criterion for supramolecular chemistry, illustrated here in the observation of molecular ordering into bilayers reminiscent of self-assembled structures commonly found in biology, including amphiphilic beta-sheet polypeptides and phospholipid bilayers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0947-6539
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2423-7
pubmed:dateRevised
2009-8-4
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Self-assembled structures with liquid-crystalline order in aqueous solution by patterning poly(phenylene ethynylene)s.
pubmed:affiliation
Polymer Science and Engineering Department, University of Massachusetts, 120 Governors Drive, Amherst, MA 01003, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural