Linked Life Data

16376263

Source:http://linkedlifedata.com/resource/pubmed/id/16376263

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2005-12-26
pubmed:abstractText
Antibiotic-impregnated bone cement beads have become popular for the treatment of osteomyelitis and/or prosthesis infection. However, bone cement has the disadvantage of heating up during polymerization of cement. Recently, calcium phosphate cement (CPC) has been used as a bone replacement and augmentation, and it does not heat up during polymerization. First, we measured the release rate of vancomycin (VCM) from bone cement and CPC impregnated with VCM for 2 weeks in vitro. The mean concentration of VCM for CPC was 62.6 times at 7 days (258 +/- 29 vs 4.12 +/- 1.0) and 6.7 times at 13 days (15.5 +/- 5.5 vs 2.3 +/- 0.7). Second, we were successful in treating 2 cases of osteomyelitis and prosthesis infection with VCM-impregnated CPC. From this study, we concluded that VCM-impregnated CPC might be an effective material for the treatment of osteomyelitis and/or prosthesis infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0883-5403
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1055-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
In vitro elution of vancomycin from calcium phosphate cement.
pubmed:affiliation
Department of Orthopaedic Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan.
pubmed:publicationType
Journal Article, In Vitro