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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-12-21
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pubmed:abstractText |
MicroRNAs (miRNAs) are 20-23 nucleotide (nt) RNA molecules that regulate gene expression post-transcriptionally. A key step toward understanding the function of the hundreds of miRNAs identified in animals is to determine their expression during development. Here we performed a detailed analysis of conditions for in situ detection of miRNAs in the zebrafish embryo using locked nucleic acid (LNA)-modified DNA probes and report expression patterns for 15 miRNAs in the mouse embryo.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1548-7091
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16369549-Animals,
pubmed-meshheading:16369549-Embryo, Mammalian,
pubmed-meshheading:16369549-Embryo, Nonmammalian,
pubmed-meshheading:16369549-Gene Expression Profiling,
pubmed-meshheading:16369549-In Situ Hybridization,
pubmed-meshheading:16369549-Mice,
pubmed-meshheading:16369549-MicroRNAs,
pubmed-meshheading:16369549-Oligonucleotide Probes,
pubmed-meshheading:16369549-Oligonucleotides,
pubmed-meshheading:16369549-Oligonucleotides, Antisense,
pubmed-meshheading:16369549-Zebrafish
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pubmed:year |
2006
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pubmed:articleTitle |
In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes.
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pubmed:affiliation |
Hubrecht Laboratory, Center for Biomedical Genetics, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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