Source:http://linkedlifedata.com/resource/pubmed/id/16337191
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2006-6-12
|
| pubmed:abstractText |
Activation of the endotoxin (LPS) receptor, CD14, leads to tumor necrosis factor-alpha (TNF) production. Plasma LPS activity is elevated in patients with severe chronic heart failure (CHF). An anti-CD14 antibody, IC14, blocks TNF production in healthy volunteers. It is not known whether IC14 prevents TNF production in CHF patients.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
1388-9842
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
366-72
|
| pubmed:dateRevised |
2011-6-8
|
| pubmed:meshHeading |
pubmed-meshheading:16337191-Aged,
pubmed-meshheading:16337191-Antigens, CD14,
pubmed-meshheading:16337191-Cardiac Output, Low,
pubmed-meshheading:16337191-Endotoxins,
pubmed-meshheading:16337191-Female,
pubmed-meshheading:16337191-Flow Cytometry,
pubmed-meshheading:16337191-Humans,
pubmed-meshheading:16337191-Male,
pubmed-meshheading:16337191-Middle Aged,
pubmed-meshheading:16337191-RNA, Messenger,
pubmed-meshheading:16337191-Tumor Necrosis Factor-alpha
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
The anti-CD14 antibody IC14 suppresses ex vivo endotoxin stimulated tumor necrosis factor-alpha in patients with chronic heart failure.
|
| pubmed:affiliation |
Clinical Cardiology, National Heart and Lung Institute, Imperial College School of Medicine, London, UK. genth@2-med.klinik.uni-mainz.de
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|