Linked Life Data

1632974

Source:http://linkedlifedata.com/resource/pubmed/id/1632974

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-8-25
pubmed:abstractText
We compared the protein tyrosine kinase (PTK) activity in the acytosolic and particulate fractions of homogenates obtained from 10 papillary thyroid adenocarcinomas with the corresponding activity in 10 specimens from adjacent normal thyroid tissue and 8 follicular adenomas. The cytosolic PTK activity of papillary adenocarcinomas was significantly elevated compared to normal and adenoma tissue. The particulate PTK activity was also significantly elevated in the papillary adenocarcinomas. The cellular distribution of PTK activity (cytosolic activity in percentage) in normal thyroid tissue, adenomas, and papillary adenocarcinomas showed no significant difference (62%, 64% and 63% respectively). These findings indicate that elevated cytosolic PTK activity may be a potentially useful marker for papillary thyroid carcinoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0284-186X
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
409-12
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Protein tyrosine kinase activity in human thyroid papillary carcinoma.
pubmed:affiliation
Second Department of Surgery, Hyogo College of Medicine, Japan.
pubmed:publicationType
Journal Article