Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19 Pt 1
pubmed:dateCreated
2005-10-5
pubmed:abstractText
We have previously shown the reactivation of some methylation-silenced genes in cancer cells by (-)-epigallocatechin-3-gallate, the major polyphenol from green tea. To determine whether other polyphenolic compounds have similar activities, we studied the effects of soy isoflavones on DNA methylation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anticarcinogenic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Azacitidine, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor..., http://linkedlifedata.com/resource/pubmed/chemical/Genistein, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxamic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Isoflavones, http://linkedlifedata.com/resource/pubmed/chemical/O(6)-Methylguanine-DNA..., http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Retinoic Acid, http://linkedlifedata.com/resource/pubmed/chemical/Sulfites, http://linkedlifedata.com/resource/pubmed/chemical/Tea, http://linkedlifedata.com/resource/pubmed/chemical/Thiocyanates, http://linkedlifedata.com/resource/pubmed/chemical/biochanin A, http://linkedlifedata.com/resource/pubmed/chemical/daidzein, http://linkedlifedata.com/resource/pubmed/chemical/decitabine, http://linkedlifedata.com/resource/pubmed/chemical/retinoic acid receptor beta, http://linkedlifedata.com/resource/pubmed/chemical/sulforafan, http://linkedlifedata.com/resource/pubmed/chemical/trichostatin A
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7033-41
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:16203797-Anticarcinogenic Agents, pubmed-meshheading:16203797-Antineoplastic Agents, pubmed-meshheading:16203797-Azacitidine, pubmed-meshheading:16203797-Carcinoma, Squamous Cell, pubmed-meshheading:16203797-Cell Line, Tumor, pubmed-meshheading:16203797-Cell Proliferation, pubmed-meshheading:16203797-Cyclin-Dependent Kinase Inhibitor p16, pubmed-meshheading:16203797-DNA Methylation, pubmed-meshheading:16203797-Dose-Response Relationship, Drug, pubmed-meshheading:16203797-Esophageal Neoplasms, pubmed-meshheading:16203797-Genistein, pubmed-meshheading:16203797-Humans, pubmed-meshheading:16203797-Hydroxamic Acids, pubmed-meshheading:16203797-Isoflavones, pubmed-meshheading:16203797-O(6)-Methylguanine-DNA Methyltransferase, pubmed-meshheading:16203797-RNA, Messenger, pubmed-meshheading:16203797-Receptors, Retinoic Acid, pubmed-meshheading:16203797-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:16203797-Soybeans, pubmed-meshheading:16203797-Sulfites, pubmed-meshheading:16203797-Tea, pubmed-meshheading:16203797-Thiocyanates
pubmed:year
2005
pubmed:articleTitle
Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.
pubmed:affiliation
Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854-8020, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, N.I.H., Extramural