Source:http://linkedlifedata.com/resource/pubmed/id/16187416
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2005-9-27
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pubmed:abstractText |
The origin of 5-HMF (5-hydroxymethyl-2-furaldehyde) in a Shengmaiyin decoction was investigated by the RP-HPLC method below. A C(18) column (250 mm x 4.6 mm, i.d. 5 microm) with a column temperature of 25 degrees C was used. The mobile phase was a mixture of ultra-pure water-acetonitrile (95:5, V/V) and the flow rate was 1.0 ml/min. The detection wavelength was 280 nm. The injection volume was 1 microl and the running time was about 20 min. The addition of Schisandra was regulated to assess the contribution of an acid environment to the production of 5-HMF. In order to confirm the role of saccharides in the production of 5-HMF, different amount of fructose was used. The 5-HMF level in decoctions of processed and unprocessed Schisandra was investigated in order to determine the origin of 5-HMF. The results showed that 5-HMF was derived mainly from the decoction of Schisandra only and not the mixed decoction of Ophionpogon and Schisandra. The appearance of 5-HMF is not simply the result of the decomposition of saccharides under the acid environment created by Schisandra, but the processing procedure plays an important role in the production of 5-HMF.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/5-hydroxymethylfurfural,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Drugs, Chinese Herbal,
http://linkedlifedata.com/resource/pubmed/chemical/Fructose,
http://linkedlifedata.com/resource/pubmed/chemical/Furaldehyde,
http://linkedlifedata.com/resource/pubmed/chemical/shengmaisan
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1673-1581
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1015-21
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16187416-Chromatography, High Pressure Liquid,
pubmed-meshheading:16187416-Drug Combinations,
pubmed-meshheading:16187416-Drugs, Chinese Herbal,
pubmed-meshheading:16187416-Fructose,
pubmed-meshheading:16187416-Furaldehyde,
pubmed-meshheading:16187416-Hydrogen-Ion Concentration,
pubmed-meshheading:16187416-Schisandra
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pubmed:year |
2005
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pubmed:articleTitle |
Investigation on the origin of 5-HMF in Shengmaiyin decoction by RP-HPLC method.
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pubmed:affiliation |
Institute of Pharmaceutical Engineering, Zhejiang University, Hangzhou 310027, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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