Source:http://linkedlifedata.com/resource/pubmed/id/16183284
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
22
|
| pubmed:dateCreated |
2005-10-5
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| pubmed:abstractText |
The 70% aqueous methanolic extract of the Peruvian plant Oryctanthus sp. was found to contain a novel saccharide of a diene alpha,omega-diacid. Compound 1 was identified as an inhibitor of the VEGF receptor. The structure of this compound was established based on NMR studies. Compound 1 inhibited ligand binding to the VEGF receptor with an IC50 of 5.0 microM.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
4907-9
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| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:16183284-Antineoplastic Agents,
pubmed-meshheading:16183284-Inhibitory Concentration 50,
pubmed-meshheading:16183284-Magnetic Resonance Spectroscopy,
pubmed-meshheading:16183284-Magnolia,
pubmed-meshheading:16183284-Molecular Structure,
pubmed-meshheading:16183284-Receptors, Vascular Endothelial Growth Factor
|
| pubmed:year |
2005
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| pubmed:articleTitle |
A new antitumor compound from the plant Oryctanthus sp. as a VEGF receptor binding inhibitor.
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| pubmed:affiliation |
Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. vinod.hegde@spcorp.com
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| pubmed:publicationType |
Journal Article
|