| pubmed-article:16141376 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16141376 | lifeskim:mentions | umls-concept:C0042401 | lld:lifeskim |
| pubmed-article:16141376 | lifeskim:mentions | umls-concept:C2936233 | lld:lifeskim |
| pubmed-article:16141376 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:16141376 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16141376 | pubmed:dateCreated | 2005-12-16 | lld:pubmed |
| pubmed-article:16141376 | pubmed:abstractText | The early (approximately 30 min) postexercise hypotension response after a session of aerobic exercise is due in part to H1-receptor-mediated vasodilation. The purpose of this study was to determine the potential contribution of H2-receptor-mediated vasodilation to postexercise hypotension. We studied 10 healthy normotensive men and women (ages 23.7 +/- 3.4 yr) before and through 90 min after a 60-min bout of cycling at 60% peak O2 uptake on randomized control and H2-receptor antagonist days (300 mg oral ranitidine). Arterial pressure (automated auscultation), cardiac output (acetylene washin) and femoral blood flow (Doppler ultrasound) were measured. Vascular conductance was calculated as flow/mean arterial pressure. Sixty minutes postexercise on the control day, femoral (delta62.3 +/- 15.6%, where Delta is change; P < 0.01) and systemic (delta13.8 +/- 5.3%; P = 0.01) vascular conductances were increased, whereas mean arterial pressure was reduced (Delta-6.7 +/- 1.1 mmHg; P < 0.01). Conversely, 60 min postexercise with ranitidine, femoral (delta9.4 +/- 9.2%; P = 0.34) and systemic (delta-2.8 +/- 4.8%; P = 0.35) vascular conductances were not elevated and mean arterial pressure was not reduced (delta-2.2 +/- 1.3 mmHg; P = 0.12). Furthermore, postexercise femoral and systemic vascular conductances were lower (P < 0.05) and mean arterial pressure was higher (P = 0.01) on the ranitidine day compared with control. Ingestion of ranitidine markedly reduces vasodilation after exercise and blunts postexercise hypotension, suggesting H2-receptor-mediated vasodilation contributes to postexercise hypotension. | lld:pubmed |
| pubmed-article:16141376 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16141376 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16141376 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16141376 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16141376 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16141376 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16141376 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16141376 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16141376 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:16141376 | pubmed:issn | 8750-7587 | lld:pubmed |
| pubmed-article:16141376 | pubmed:author | pubmed-author:HalliwillJohn... | lld:pubmed |
| pubmed-article:16141376 | pubmed:author | pubmed-author:McCordJennife... | lld:pubmed |
| pubmed-article:16141376 | pubmed:author | pubmed-author:BeasleyJulie... | lld:pubmed |
| pubmed-article:16141376 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16141376 | pubmed:volume | 100 | lld:pubmed |
| pubmed-article:16141376 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16141376 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16141376 | pubmed:pagination | 67-75 | lld:pubmed |
| pubmed-article:16141376 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:16141376 | pubmed:meshHeading | pubmed-meshheading:16141376... | lld:pubmed |
| pubmed-article:16141376 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16141376 | pubmed:articleTitle | H2-receptor-mediated vasodilation contributes to postexercise hypotension. | lld:pubmed |
| pubmed-article:16141376 | pubmed:affiliation | Department of Human Physiology, 122 Esslinger Hall, 1240 University of Oregon, Eugene, Oregon 97403-1240, USA. | lld:pubmed |
| pubmed-article:16141376 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16141376 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:16141376 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16141376 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16141376 | lld:pubmed |
