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pubmed-article:1609092pubmed:abstractTextA three-dimensional system for dosimetric calculation of radiation from interstitial brachytherapeutic implants was developed and was compared with conventional dosimetry performed with a commercial two-dimensional system. Software programs written for this study enabled the authors to place radioactive sources in the correct reconstructed anatomic locations, compute the isodose distribution around these sources, and display the isodose curves in their correct relationship to anatomic structures. Eight radiation oncologists evaluated the usefulness of both systems. Verification studies in phantoms and in 20 patients with gold-198 implants in the prostate gland showed that the experimental system was very accurate in volume reconstruction, seed localization, isodose distribution, point-dose calculation, and computation of dose-volume histograms. Although the dose depictions in the two systems matched almost exactly, statistically significant differences existed in interpretation of the dosimetric data generated by both systems. For example, the oncologists consistently believed that the dose to the prostate was lower when the three-dimensional system was used (P less than or equal to .0001).lld:pubmed
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pubmed-article:1609092pubmed:authorpubmed-author:AndersonK MKMlld:pubmed
pubmed-article:1609092pubmed:authorpubmed-author:HusseyD HDHlld:pubmed
pubmed-article:1609092pubmed:authorpubmed-author:BerbaumK SKSlld:pubmed
pubmed-article:1609092pubmed:authorpubmed-author:AvizonisV NVNlld:pubmed
pubmed-article:1609092pubmed:authorpubmed-author:JaniS KSKlld:pubmed
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pubmed-article:1609092pubmed:dateRevised2007-11-15lld:pubmed
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pubmed-article:1609092pubmed:year1992lld:pubmed
pubmed-article:1609092pubmed:articleTitleThree-dimensional viewing of and dosimetric calculations in Au-198 implants of the prostate.lld:pubmed
pubmed-article:1609092pubmed:affiliationDivision of Radiation Oncology, University of Iowa College of Medicine, Iowa City.lld:pubmed
pubmed-article:1609092pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:1609092pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:1609092pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed