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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1992-7-23
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pubmed:abstractText |
Bilateral microinjection of ethanol to the preoptic area of rats causes a dose-dependent hypnotic effect at doses that do not affect brain temperature. Rats were polygraphically recorded for 6 h, and brain temperature was recorded every 10 min for 3 h. Administration of 0.047 mumol ethanol increased total sleep during the 3-6 h interval, while 0.24 and 0.47 mumol ethanol increased deep slow-wave sleep (SWS2) and total sleep during the 3-6- and 0-6-h intervals. The 0.24-mumol ethanol microinjections also increased REM sleep for the 0-6-h interval. No changes in sleep latencies were observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0741-8329
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
275-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1605895-Animals,
pubmed-meshheading:1605895-Body Temperature,
pubmed-meshheading:1605895-Dose-Response Relationship, Drug,
pubmed-meshheading:1605895-Ethanol,
pubmed-meshheading:1605895-Male,
pubmed-meshheading:1605895-Microinjections,
pubmed-meshheading:1605895-Preoptic Area,
pubmed-meshheading:1605895-Rats,
pubmed-meshheading:1605895-Rats, Inbred Strains,
pubmed-meshheading:1605895-Sleep,
pubmed-meshheading:1605895-Sodium Chloride,
pubmed-meshheading:1605895-Time Factors
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pubmed:articleTitle |
Effects of ethanol injection to the preoptic area on sleep and temperature in rats.
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pubmed:affiliation |
Department of Pharmacology, College of Medicine University of Illinois, Chicago 60612.
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pubmed:publicationType |
Journal Article
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