| pubmed-article:16054321 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C0302908 | lld:lifeskim |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C0037813 | lld:lifeskim |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:16054321 | lifeskim:mentions | umls-concept:C0064993 | lld:lifeskim |
| pubmed-article:16054321 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:16054321 | pubmed:dateCreated | 2005-10-14 | lld:pubmed |
| pubmed-article:16054321 | pubmed:abstractText | A simple, sensitive and selective liquid chromatography coupled with electrospray ionization mass spectrometry (LC/ESI/MS) method for determination of limonin (LM) in rat plasma has been developed and validated. The method had advantages of a single liquid-liquid extraction with ether and high sensitivity. Analyses were conducted at a flow rate of 0.2 ml/min by a gradient elution. The detection utilized selected ion monitoring in the negative ion mode at m/z 460.00 and 423.15 for the deprotonated molecular ions of LM and the internal standard, respectively. The quantitation limit for LM in rat plasma was 1.0 ng/ml. The linearity was also excellent over the concentration range of 1.9-500 ng/ml of LM. The intra- and inter-day precision (relative standard deviation (R.S.D.%)) was lower than 10% and accuracy ranged from 90 to 110%, showing a good reproducibility. This developed method was successfully applied to analysis of LM in biological fluids. | lld:pubmed |
| pubmed-article:16054321 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16054321 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16054321 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16054321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16054321 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16054321 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16054321 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:16054321 | pubmed:issn | 0731-7085 | lld:pubmed |
| pubmed-article:16054321 | pubmed:author | pubmed-author:SzeS HSH | lld:pubmed |
| pubmed-article:16054321 | pubmed:author | pubmed-author:LuTongT | lld:pubmed |
| pubmed-article:16054321 | pubmed:author | pubmed-author:WangGuang-JiG... | lld:pubmed |
| pubmed-article:16054321 | pubmed:author | pubmed-author:LiangYanY | lld:pubmed |
| pubmed-article:16054321 | pubmed:author | pubmed-author:LiuXiao-DongX... | lld:pubmed |
| pubmed-article:16054321 | pubmed:author | pubmed-author:HuYu-ZhuYZ | lld:pubmed |
| pubmed-article:16054321 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16054321 | pubmed:day | 4 | lld:pubmed |
| pubmed-article:16054321 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:16054321 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16054321 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16054321 | pubmed:pagination | 1031-5 | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:meshHeading | pubmed-meshheading:16054321... | lld:pubmed |
| pubmed-article:16054321 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16054321 | pubmed:articleTitle | Determination of limonin in rat plasma by liquid chromatography-electrospray mass spectrometry. | lld:pubmed |
| pubmed-article:16054321 | pubmed:affiliation | China Pharmaceutical University, Shennong Road No. 1, Nanjning 210038, China. | lld:pubmed |
| pubmed-article:16054321 | pubmed:publicationType | Journal Article | lld:pubmed |
