Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-7-4
pubmed:abstractText
Presence of a nasogastric tube is a risk factor for the development of ventilator-associated pneumonia (VAP). Alternatively, gastrostomy can be used for administration of enteral feedings. To determine whether early performance of gastrostomy affects frequency of VAP, a randomised, controlled study was carried out in patients mechanically ventilated for stroke or head injury. In the gastrostomy group, patients underwent the procedure within 24 h of intubation. A nasogastric tube was inserted in controls. Individual subjects were studied for 3 weeks. In total, 20 subjects (mean age 48+/-15.2 yrs) were allocated to the gastrostomy group, and 21 to the control group (46.6+/-15.4 yrs). Of these groups, two (10%) and eight (38.1%) developed VAP, respectively. Four patients with gastrostomy and three controls did not complete the study (due to weaning from ventilatory support or death). After excluding these subjects, difference in VAP frequency persisted: two out of 16 subjects with gastrostomy had VAP (12.5%) versus eight out of 18 controls (44.4%). There were no differences in duration of hospitalisation or mortality between the two groups. In conclusion, in patients mechanically ventilated for stroke or head injury early gastrostomy is associated with a lower frequency of ventilator-associated pneumonia compared with a nasogastric tube.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0903-1936
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
106-11
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:15994396-APACHE, pubmed-meshheading:15994396-Adult, pubmed-meshheading:15994396-Age Distribution, pubmed-meshheading:15994396-Case-Control Studies, pubmed-meshheading:15994396-Chi-Square Distribution, pubmed-meshheading:15994396-Cohort Studies, pubmed-meshheading:15994396-Craniocerebral Trauma, pubmed-meshheading:15994396-Critical Illness, pubmed-meshheading:15994396-Cross Infection, pubmed-meshheading:15994396-Female, pubmed-meshheading:15994396-Gastrostomy, pubmed-meshheading:15994396-Glasgow Coma Scale, pubmed-meshheading:15994396-Humans, pubmed-meshheading:15994396-Incidence, pubmed-meshheading:15994396-Injury Severity Score, pubmed-meshheading:15994396-Male, pubmed-meshheading:15994396-Middle Aged, pubmed-meshheading:15994396-Pneumonia, Bacterial, pubmed-meshheading:15994396-Probability, pubmed-meshheading:15994396-Prognosis, pubmed-meshheading:15994396-Reference Values, pubmed-meshheading:15994396-Respiration, Artificial, pubmed-meshheading:15994396-Risk Assessment, pubmed-meshheading:15994396-Sex Distribution, pubmed-meshheading:15994396-Stroke, pubmed-meshheading:15994396-Time Factors, pubmed-meshheading:15994396-Treatment Outcome
pubmed:year
2005
pubmed:articleTitle
Early gastrostomy reduces the rate of ventilator-associated pneumonia in stroke or head injury patients.
pubmed:affiliation
University of Thessaly School of Medicine and Larissa University Hospital, Dept of Critical Care Medicine, P.O. Box 1425, Larissa 41110, Greece. elenikostadima@yahoo.gr
pubmed:publicationType
Journal Article, Comparative Study, Randomized Controlled Trial