Source:http://linkedlifedata.com/resource/pubmed/id/15990740
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2005-7-1
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| pubmed:abstractText |
BACKGROUND: Cardiac resynchronization therapy (CRT) is currently indicated in patients with moderate to severe heart failure, a wide QRS complex and significant left ventricular dysfunction despite optimal medical therapy. Adoption of these criteria for CRT results in a favorable response in only two thirds of candidates. METHODS: "Predictors of response to cardiac resynchronization therapy (PROSPECT)," a prospective, multicenter, nonrandomized study, aims to identify echocardiographic measures of dyssynchrony and evaluate their ability to predict response to CRT. PROSPECT will enroll approximately 300 patients in up to 75 centers in the United States, Asia, and Europe with clinical follow-up for 6 months. We will prospectively and individually test a variety of conventional echocardiographic and tissue Doppler imaging parameters against measures of clinical response. The primary response criteria are improvement in the heart failure Clinical Composite Score and left ventricular reverse remodeling. Enrollment began in March 2004 and is expected to conclude early 2005.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
1097-6744
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| pubmed:author |
pubmed-author:AbrahamWilliam TWT,
pubmed-author:BaxJeroenJ,
pubmed-author:ChungEugeneE,
pubmed-author:FedewaMichelleM,
pubmed-author:GhioStefanoS,
pubmed-author:LeónAngel RAR,
pubmed-author:LeclercqChristopheC,
pubmed-author:MerlinoJohnJ,
pubmed-author:NihoyannopoulosPetrosP,
pubmed-author:NotabartoloDeanD,
pubmed-author:PROSPECT Investigators,
pubmed-author:SunJing PingJP,
pubmed-author:TavazziLuigiL,
pubmed-author:YuCheuk-ManCM
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| pubmed:issnType |
Electronic
|
| pubmed:volume |
149
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
600-5
|
| pubmed:dateRevised |
2007-11-15
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| pubmed:meshHeading |
pubmed-meshheading:15990740-Asia,
pubmed-meshheading:15990740-Echocardiography, Doppler,
pubmed-meshheading:15990740-Electric Countershock,
pubmed-meshheading:15990740-Endpoint Determination,
pubmed-meshheading:15990740-Europe,
pubmed-meshheading:15990740-Forecasting,
pubmed-meshheading:15990740-Heart Failure,
pubmed-meshheading:15990740-Humans,
pubmed-meshheading:15990740-Patient Selection,
pubmed-meshheading:15990740-Prospective Studies,
pubmed-meshheading:15990740-Quality of Life,
pubmed-meshheading:15990740-Research Design,
pubmed-meshheading:15990740-Sample Size,
pubmed-meshheading:15990740-Treatment Outcome,
pubmed-meshheading:15990740-United States,
pubmed-meshheading:15990740-Ventricular Dysfunction, Left,
pubmed-meshheading:15990740-Ventricular Function, Left,
pubmed-meshheading:15990740-Ventricular Remodeling
|
| pubmed:year |
2005
|
| pubmed:articleTitle |
Predictors of response to cardiac resynchronization therapy (PROSPECT)--study design.
|
| pubmed:affiliation |
Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong. cmyu@cuhk.edu.hk
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
|