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pubmed-article:15947478pubmed:abstractTextEosinophils are generally recognized as effector cells in asthma. Recently, neutrophils have been suggested to contribute to the development of chronic severe asthma. The mechanisms by which neutrophils contribute to the pathophysiology of asthma remain to be elucidated; however, neutrophils may affect either accumulation or functional status of eosinophils via the generation of inflammatory mediators. The objective of this study was to evaluate whether neutrophilic inflammation is associated with eosinophilic inflammation in severe asthma.lld:pubmed
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pubmed-article:15947478pubmed:copyrightInfoCopyright 2005 S. Karger AG, Basel.lld:pubmed
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pubmed-article:15947478pubmed:articleTitleAssociation between neutrophilic and eosinophilic inflammation in patients with severe persistent asthma.lld:pubmed
pubmed-article:15947478pubmed:affiliationDepartment of Respiratory Medicine, Saitama Medical School, Japan.lld:pubmed
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