Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-6-7
pubmed:abstractText
High-dose rate endorectal brachytherapy (HDR-EBT) is mainly used as a palliative treatment modality. In this paper, we compare dosimetry distributions for a single-channel catheter (Miami) applicator with distributions of the inflatable multichannel (Novi Sad) endorectal applicator. The comparisons were made with respect to dose coverage to the clinical tumor volume as well as to the bladder, rectal wall, prostate, and bone marrow. Our results suggest that a multichannel applicator provides better sparing of the bone marrow by 50%, clinically uninvolved parts of the rectal wall by 70%, and bladder and prostate (in the case of male patients) by 100% in terms of ratio of median doses to critical organ volume for single- and multichannel endorectal applicators. Our results justify the advantage of using a multichannel endorectal brachytherapy applicator as a neo-adjuvant treatment of patients with locally advanced rectal cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1526-9914
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
44-9
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:15940211-Balloon Dilation, pubmed-meshheading:15940211-Body Burden, pubmed-meshheading:15940211-Brachytherapy, pubmed-meshheading:15940211-Computer Simulation, pubmed-meshheading:15940211-Equipment Design, pubmed-meshheading:15940211-Equipment Failure Analysis, pubmed-meshheading:15940211-Humans, pubmed-meshheading:15940211-Models, Biological, pubmed-meshheading:15940211-Organ Specificity, pubmed-meshheading:15940211-Palliative Care, pubmed-meshheading:15940211-Radiation Injuries, pubmed-meshheading:15940211-Radiation Protection, pubmed-meshheading:15940211-Radiometry, pubmed-meshheading:15940211-Radiotherapy, Adjuvant, pubmed-meshheading:15940211-Radiotherapy Dosage, pubmed-meshheading:15940211-Radiotherapy Planning, Computer-Assisted, pubmed-meshheading:15940211-Rectal Neoplasms, pubmed-meshheading:15940211-Relative Biological Effectiveness, pubmed-meshheading:15940211-Risk Assessment, pubmed-meshheading:15940211-Risk Factors, pubmed-meshheading:15940211-Treatment Outcome
pubmed:year
2005
pubmed:articleTitle
Advantages of inflatable multichannel endorectal applicator in the neo-adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy.
pubmed:affiliation
Medical Physics Department, McGill University Health Centre, Montreal, Quebec, H3G 1A4, Canada. devic@medphys.mcgill.ca
pubmed:publicationType
Journal Article, Comparative Study, Evaluation Studies