|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
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|
pubmed:dateCreated |
1992-6-26
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|
pubmed:abstractText |
This study identifies eight patients who during routine therapy with conventional doses of tricyclic antidepressants (TCAs) experienced elevated plasma concentrations and suffered a grand mal seizure. We correlate the incidence of TCA-induced seizures with TCA plasma level and suggest that the incidence of TCA-induced seizures can be significantly reduced with the judicious use of therapeutic drug monitoring.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0160-6689
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
53
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
160-2
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|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1592842-Adult,
pubmed-meshheading:1592842-Ambulatory Care,
pubmed-meshheading:1592842-Amitriptyline,
pubmed-meshheading:1592842-Antidepressive Agents, Tricyclic,
pubmed-meshheading:1592842-Depressive Disorder,
pubmed-meshheading:1592842-Desipramine,
pubmed-meshheading:1592842-Drug Administration Schedule,
pubmed-meshheading:1592842-Drug Monitoring,
pubmed-meshheading:1592842-Epilepsy, Tonic-Clonic,
pubmed-meshheading:1592842-Female,
pubmed-meshheading:1592842-Hospitalization,
pubmed-meshheading:1592842-Humans,
pubmed-meshheading:1592842-Imipramine,
pubmed-meshheading:1592842-Incidence,
pubmed-meshheading:1592842-Male,
pubmed-meshheading:1592842-Middle Aged,
pubmed-meshheading:1592842-Panic Disorder
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|
pubmed:year |
1992
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|
pubmed:articleTitle |
Tricyclic antidepressant-induced seizures and plasma drug concentration.
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|
pubmed:affiliation |
Department of Psychiatry, University of Kansas School of Medicine-Wichita.
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pubmed:publicationType |
Journal Article
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