Source:http://linkedlifedata.com/resource/pubmed/id/15863311
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2005-5-2
|
| pubmed:abstractText |
anti-Substituted beta-methylphenylalanine derived amides have been shown to be potent DPP-IV inhibitors exhibiting excellent selectivity over both DPP8 and DPP9. These are among the most potent compounds reported to date lacking an electrophilic trap. The most potent compound among these is 5-oxo-1,2,4-oxadiazole 44, which is a 3 nM DPP-IV inhibitor.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0960-894X
|
| pubmed:author |
pubmed-author:HeHuaibingH,
pubmed-author:HeJiafangJ,
pubmed-author:LeitingBarbaraB,
pubmed-author:LyonsKathryn AKA,
pubmed-author:MarsilioFrankF,
pubmed-author:MathvinkRobertR,
pubmed-author:ParkYou-JungYJ,
pubmed-author:PatelReshma ARA,
pubmed-author:ThornberryNancy ANA,
pubmed-author:WeberAnn EAE,
pubmed-author:WeiLanL,
pubmed-author:WuJoseph KJK,
pubmed-author:XuJinyouJ
|
| pubmed:issnType |
Print
|
| pubmed:day |
16
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2533-6
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading | |
| pubmed:year |
2005
|
| pubmed:articleTitle |
Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors.
|
| pubmed:affiliation |
Department of Medicinal Chemistry, Merck & Co., Inc., PO Box 2000, Rahway, NJ 07065, USA.
|
| pubmed:publicationType |
Journal Article
|