Source:http://linkedlifedata.com/resource/pubmed/id/15863009
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2005-5-2
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pubmed:abstractText |
Three diterpene compounds isolated from the anti-cancer herbal medicine kansui, namely, kansuinin B, 20-OD-ingenol Z, and 20-OD-ingenol E, specifically inhibited the proliferation of isolated embryonic cells from Xenopus embryos. We conducted a cytologic study to determine the mechanism underlying the arrest of the cellular proliferation by these compounds. While kansuinin B and 20-OD-ingenol Z treatment decreased the cell numbers in the S phase and the M phase substages of the cell cycle, 20-OD-ingenol E inhibited mitosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0968-0896
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3847-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15863009-Animals,
pubmed-meshheading:15863009-Cell Division,
pubmed-meshheading:15863009-Cells, Cultured,
pubmed-meshheading:15863009-Diterpenes,
pubmed-meshheading:15863009-Female,
pubmed-meshheading:15863009-Male,
pubmed-meshheading:15863009-S Phase,
pubmed-meshheading:15863009-Xenopus laevis
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pubmed:year |
2005
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pubmed:articleTitle |
Mechanism of proliferation arrest of embryonic cells of Xenopus by diterpene compounds.
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pubmed:affiliation |
Laboratory of Biochemistry, Department of Chemistry, College of Humanities and Sciences, Nihon University, 3-25-40 Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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