Linked Life Data

1583385

Source:http://linkedlifedata.com/resource/pubmed/id/1583385

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-6-16
pubmed:abstractText
The fecal osmotic gap is considered to be useful in the investigation of chronic diarrhea. However, two important questions regarding the calculation of the osmotic gap remain unanswered: the effect of the method of measuring osmolality and the most appropriate means for its calculation. In 41 patients with varying causes of diarrhea, stool osmolalities and electrolyte concentrations were measured. Measurement of stool osmolality by a dew point technique underestimated results by a variable factor, which makes it an inappropriate method. Fecal osmolality measured by freezing point depression gave reliable results and so was considered to be preferable. The osmotic gap was calculated by two methods: subtraction of the calculated osmolality from (1) stool osmolality and (2) plasma osmolality. The former approach was found to be inappropriate on the basis of large variations in results when consecutive stool samples were analyzed, a poor correlation with the severity of osmotic diarrhea, poor resolution between results from patients with secretory diarrhea and those with osmotic diarrhea, and practical difficulties in ensuring adequate collection of stool samples.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-2143
pubmed:author
pubmed:issnType
Print
pubmed:volume
119
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-63
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
The fecal osmotic gap: technical aspects regarding its calculation.
pubmed:affiliation
Gastroenterology Unit, Royal Infirmary, Glasgow, Scotland.
pubmed:publicationType
Journal Article