Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-4-8
pubmed:abstractText
To identify tobacco recidivism among 86 heart transplant recipients who were smokers but demonstrated compliance with a smoking cessation program pre-transplant, we used a questionnaire and randomly tested urine for nicotine and its by-products. In 36 patients, we also evaluated circulating levels of HS-CRP, homocysteine and MPV. Twenty-eight (32.5%) of 86 patients met our definition for tobacco exposure. In this cohort, 28 (32.5%) of 86 patients met our definition for tobacco exposure. Of these 28, 12 patients self-reported tobacco use and demonstrated biochemical verification; 14 patients demonstrated only biochemical evidence of significant tobacco exposure; 2 patients self-reported tobacco use but did not demonstrate biochemical positivity. Smoking cessation within 6 months of transplantation (r = 0.52) and time post-transplantation (r = 0.43) were independent predictors for recidivism of tobacco use, p < 0.01. No differences in HS-CRP, homocysteine and MPV levels were noted among the groups. Our investigation demonstrates a high rate of tobacco recidivism among heart transplant recipients, yet few admit to it. The adverse effects of tobacco do not appear to be directly modulated by an effect on athero-thrombotic risk markers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1600-6135
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1137-40
pubmed:dateRevised
2007-2-14
pubmed:meshHeading
pubmed-meshheading:15816897-Adult, pubmed-meshheading:15816897-Aged, pubmed-meshheading:15816897-Biological Markers, pubmed-meshheading:15816897-C-Reactive Protein, pubmed-meshheading:15816897-Cardiovascular Diseases, pubmed-meshheading:15816897-Cohort Studies, pubmed-meshheading:15816897-Female, pubmed-meshheading:15816897-Heart Transplantation, pubmed-meshheading:15816897-Homocysteine, pubmed-meshheading:15816897-Humans, pubmed-meshheading:15816897-Male, pubmed-meshheading:15816897-Middle Aged, pubmed-meshheading:15816897-Multivariate Analysis, pubmed-meshheading:15816897-Questionnaires, pubmed-meshheading:15816897-Risk, pubmed-meshheading:15816897-Risk Factors, pubmed-meshheading:15816897-Smoking, pubmed-meshheading:15816897-Smoking Cessation, pubmed-meshheading:15816897-Thrombosis, pubmed-meshheading:15816897-Time Factors, pubmed-meshheading:15816897-Tobacco
pubmed:year
2005
pubmed:articleTitle
Recrudescent tobacco exposure following heart transplantation: clinical profiles and relationship with athero-thrombosis risk markers.
pubmed:affiliation
The Cardiomyopathy and Heart Transplantation Center, Ochsner Clinic Foundation, New Orleans, LA, USA. mmehra@ochsner.org
pubmed:publicationType
Journal Article