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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2005-3-9
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pubmed:abstractText |
in acromegaly, the criteria for the cure of the disease after neurosurgery have become tighter and tighter. In contrast, the evaluation of control of disease activity during medical treatment is based upon the normalisation of IGF-I levels and epidemiological criteria, i.e. lessening GH (assessed by RIA) to levels reported to normalise increased mortality. The aim of this study was to evaluate GH and IGF-I suppression during prolonged SS analogues (SA) treatment. The concordance between "safe" GH and normalised IGF-I levels during SA was also assessed, according to gender and gonadal status.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0391-4097
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1040-7
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pubmed:meshHeading |
pubmed-meshheading:15754736-Acromegaly,
pubmed-meshheading:15754736-Adult,
pubmed-meshheading:15754736-Aged,
pubmed-meshheading:15754736-Aged, 80 and over,
pubmed-meshheading:15754736-Biological Markers,
pubmed-meshheading:15754736-Cohort Studies,
pubmed-meshheading:15754736-Endpoint Determination,
pubmed-meshheading:15754736-Female,
pubmed-meshheading:15754736-Human Growth Hormone,
pubmed-meshheading:15754736-Humans,
pubmed-meshheading:15754736-Insulin-Like Growth Factor I,
pubmed-meshheading:15754736-Male,
pubmed-meshheading:15754736-Middle Aged,
pubmed-meshheading:15754736-Postmenopause,
pubmed-meshheading:15754736-Prognosis,
pubmed-meshheading:15754736-Retrospective Studies,
pubmed-meshheading:15754736-Sensitivity and Specificity,
pubmed-meshheading:15754736-Sex Factors,
pubmed-meshheading:15754736-Somatostatin
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pubmed:year |
2004
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pubmed:articleTitle |
Treatment of acromegaly with SS analogues: should GH and IGF-I target levels be lowered to assert a tight control of the disease?
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pubmed:affiliation |
Division of Endocrinology, Niguarda Hospital, Milan, Italy. renatocozzi@tiscali.it
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Multicenter Study
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