15729167

Source:http://linkedlifedata.com/resource/pubmed/id/15729167

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0010592, umls-concept:C0017337, umls-concept:C0205191, umls-concept:C0298067, umls-concept:C0599918, umls-concept:C1280500
pubmed:issue	4
pubmed:dateCreated	2005-2-24
pubmed:abstractText	: Apoptosis was shown to play a role in the progression of fibrosis in a chronic cyclosporine A (CsA) nephrotoxicity animal model. In addition, the antifibrotic molecule pirfenidone (PFD) was shown to ameliorate fibrosis in this model. We evaluated the role of PFD on the expression of apoptosis-regulatory genes in the kidneys of CsA-treated rats.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0132144
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Bcl2l1 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Casp3 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Caspase 3, http://linkedlifedata.com/resource/pubmed/chemical/Caspases, http://linkedlifedata.com/resource/pubmed/chemical/Cyclosporine, http://linkedlifedata.com/resource/pubmed/chemical/Fas Ligand Protein, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2, http://linkedlifedata.com/resource/pubmed/chemical/Pyridones, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Tnfsf6 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/bcl-X Protein, http://linkedlifedata.com/resource/pubmed/chemical/pirfenidone
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	0041-1337
pubmed:author	pubmed-author:AndohTakeshi FTF, pubmed-author:BennettWilliam MWM, pubmed-author:IOVAAA, pubmed-author:ShihabFuad SFS
pubmed:issnType	Print
pubmed:day	27
pubmed:volume	79
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	419-26
pubmed:dateRevised	2010-3-24
pubmed:meshHeading	pubmed-meshheading:15729167-Animals, pubmed-meshheading:15729167-Apoptosis, pubmed-meshheading:15729167-Caspase 3, pubmed-meshheading:15729167-Caspases, pubmed-meshheading:15729167-Cyclosporine, pubmed-meshheading:15729167-Fas Ligand Protein, pubmed-meshheading:15729167-Gene Expression Regulation, pubmed-meshheading:15729167-Genes, p53, pubmed-meshheading:15729167-In Situ Nick-End Labeling, pubmed-meshheading:15729167-Kidney, pubmed-meshheading:15729167-Male, pubmed-meshheading:15729167-Membrane Glycoproteins, pubmed-meshheading:15729167-Proto-Oncogene Proteins c-bcl-2, pubmed-meshheading:15729167-Pyridones, pubmed-meshheading:15729167-RNA, Messenger, pubmed-meshheading:15729167-Rats, pubmed-meshheading:15729167-Rats, Sprague-Dawley, pubmed-meshheading:15729167-bcl-X Protein
pubmed:year	2005
pubmed:articleTitle	Effect of pirfenidone on apoptosis-regulatory genes in chronic cyclosporine nephrotoxicity.
pubmed:affiliation	Division of Nephrology, University of Utah School of Medicine, 30 N. 1900 E., Salt Lake City, UT 84132, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't