15728539

Source:http://linkedlifedata.com/resource/pubmed/id/15728539

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0013090, umls-concept:C0086418, umls-concept:C0752312, umls-concept:C1182610, umls-concept:C1370600, umls-concept:C1704259, umls-concept:C1705987
pubmed:issue	3
pubmed:dateCreated	2005-2-24
pubmed:abstractText	To evaluate the effects of TGF-beta1 and doxycycline on production of gelatinase MMP-9 and activation of Smad, c-Jun N-terminal kinase (JNK), extracellular-regulated kinase (ERK), and p38 mitogen-activated protein kinase (MAPK) signaling pathways in human corneal epithelial cells.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/EY014553, http://linkedlifedata.com/resource/pubmed/grant/EY11915
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7703701
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Doxycycline, http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP..., http://linkedlifedata.com/resource/pubmed/chemical/JNK Mitogen-Activated Protein..., http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/SMAD2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Smad2 Protein, http://linkedlifedata.com/resource/pubmed/chemical/TGFB1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators, http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta, http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta1, http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0146-0404
pubmed:author	pubmed-author:KimHyun-SeungHS, pubmed-author:LiDe-QuanDQ, pubmed-author:LuoLihuiL, pubmed-author:PflugfelderStephen CSC
pubmed:issnType	Print
pubmed:volume	46
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	840-8
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:15728539-Anti-Bacterial Agents, pubmed-meshheading:15728539-Blotting, Northern, pubmed-meshheading:15728539-Blotting, Western, pubmed-meshheading:15728539-Cells, Cultured, pubmed-meshheading:15728539-DNA-Binding Proteins, pubmed-meshheading:15728539-Dose-Response Relationship, Drug, pubmed-meshheading:15728539-Doxycycline, pubmed-meshheading:15728539-Epithelium, Corneal, pubmed-meshheading:15728539-Extracellular Signal-Regulated MAP Kinases, pubmed-meshheading:15728539-Humans, pubmed-meshheading:15728539-JNK Mitogen-Activated Protein Kinases, pubmed-meshheading:15728539-Matrix Metalloproteinase 9, pubmed-meshheading:15728539-Mitogen-Activated Protein Kinases, pubmed-meshheading:15728539-RNA, Messenger, pubmed-meshheading:15728539-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:15728539-Signal Transduction, pubmed-meshheading:15728539-Smad2 Protein, pubmed-meshheading:15728539-Trans-Activators, pubmed-meshheading:15728539-Transforming Growth Factor beta, pubmed-meshheading:15728539-Transforming Growth Factor beta1, pubmed-meshheading:15728539-p38 Mitogen-Activated Protein Kinases
pubmed:year	2005
pubmed:articleTitle	Doxycycline inhibits TGF-beta1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells.
pubmed:affiliation	Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't