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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-2-8
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pubmed:abstractText |
The renin-angiotensin system has been implicated in the pathogenesis of fibrosis in various organs. However, its involvement in peritoneal fibrosis, a crucial complication of peritoneal dialysis, is unclear. Human peritoneal mesothelial cells (HPMC) play a major role in peritoneal fibrosis by producing extracellular matrix (ECM). However, there is scant data regarding the effect of angiotensin II (Ang II) on ECM expression and signal transduction pathways in HPMC.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1126-35
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15698454-Angiotensin II,
pubmed-meshheading:15698454-Cells, Cultured,
pubmed-meshheading:15698454-Epithelial Cells,
pubmed-meshheading:15698454-Female,
pubmed-meshheading:15698454-Fibronectins,
pubmed-meshheading:15698454-Gene Expression Regulation,
pubmed-meshheading:15698454-Humans,
pubmed-meshheading:15698454-Male,
pubmed-meshheading:15698454-Middle Aged,
pubmed-meshheading:15698454-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:15698454-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:15698454-Peritoneal Dialysis, Continuous Ambulatory,
pubmed-meshheading:15698454-Peritoneum,
pubmed-meshheading:15698454-Peritonitis,
pubmed-meshheading:15698454-Receptors, Angiotensin,
pubmed-meshheading:15698454-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2005
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pubmed:articleTitle |
Angiotensin II induces fibronectin expression in human peritoneal mesothelial cells via ERK1/2 and p38 MAPK.
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pubmed:affiliation |
Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. kkiri@hiroshima-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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