|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0205419,
umls-concept:C0442821,
umls-concept:C0596244,
umls-concept:C1334089,
umls-concept:C1334140,
umls-concept:C1334141,
umls-concept:C1337112,
umls-concept:C1516518,
umls-concept:C1882417,
umls-concept:C1954276
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|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2005-5-30
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|
pubmed:abstractText |
As cellular proliferation is central to the carcinogenic process, pathways that regulate proliferation may be important. Therefore, genes in the insulin and the insulin-like growth factor signaling pathways are plausible candidates for susceptibility genes for prostate cancer. We hypothesized that functional polymorphisms in INS, IRS1, IRS2, and IGF1 may be associated with prostate cancer.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0270-4137
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|
pubmed:author |
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pubmed:copyrightInfo |
(c) 2005 Wiley-Liss, Inc.
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|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
64
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
168-74
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pubmed:dateRevised |
2011-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:15678496-Adult,
pubmed-meshheading:15678496-Aged,
pubmed-meshheading:15678496-Case-Control Studies,
pubmed-meshheading:15678496-Humans,
pubmed-meshheading:15678496-Insulin,
pubmed-meshheading:15678496-Insulin Receptor Substrate Proteins,
pubmed-meshheading:15678496-Insulin-Like Growth Factor I,
pubmed-meshheading:15678496-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:15678496-Male,
pubmed-meshheading:15678496-Middle Aged,
pubmed-meshheading:15678496-Phosphoproteins,
pubmed-meshheading:15678496-Polymorphism, Genetic,
pubmed-meshheading:15678496-Prostatic Neoplasms,
pubmed-meshheading:15678496-Risk Factors
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Prostate cancer risk and IRS1, IRS2, IGF1, and INS polymorphisms: strong association of IRS1 G972R variant and cancer risk.
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|
pubmed:affiliation |
Department of Medicine, Division of Epidemiology, University of California Irvine, Irvine, CA 92697-7550, USA. sneuhaus@uci.edu
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
