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pubmed-article:15633126pubmed:abstractTextHepatocellular carcinoma (HCC) is one of the most common human malignancies. Its high mortality rate is mainly a result of high intrahepatic recurrence. The novel synthetic retinoid acyclic retinoid (ACR) has been reported to prevent the recurrence of human HCC after surgical resection of primary tumors, but the molecular mechanisms underlying its effects remain to be elucidated. In this study, we clarified the molecular targets of ACR.lld:pubmed
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pubmed-article:15633126pubmed:dateRevised2009-11-19lld:pubmed
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pubmed-article:15633126pubmed:articleTitleAcyclic retinoid inhibits human hepatoma cell growth by suppressing fibroblast growth factor-mediated signaling pathways.lld:pubmed
pubmed-article:15633126pubmed:affiliationDepartment of Gastroenterology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.lld:pubmed
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