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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-5
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pubmed:abstractText |
Hepatocellular carcinoma (HCC) is one of the most common human malignancies. Its high mortality rate is mainly a result of high intrahepatic recurrence. The novel synthetic retinoid acyclic retinoid (ACR) has been reported to prevent the recurrence of human HCC after surgical resection of primary tumors, but the molecular mechanisms underlying its effects remain to be elucidated. In this study, we clarified the molecular targets of ACR.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3,7,11,15-tetramethyl-2,4,6,10,14-he...,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/FGFR3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Fibroblast Growth...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fibroblast Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Tretinoin,
http://linkedlifedata.com/resource/pubmed/chemical/rho GTP-Binding Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
86-95
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15633126-Antineoplastic Agents,
pubmed-meshheading:15633126-Carcinoma, Hepatocellular,
pubmed-meshheading:15633126-Cell Line, Tumor,
pubmed-meshheading:15633126-Cell Proliferation,
pubmed-meshheading:15633126-Down-Regulation,
pubmed-meshheading:15633126-Fibroblast Growth Factors,
pubmed-meshheading:15633126-Gene Expression,
pubmed-meshheading:15633126-Humans,
pubmed-meshheading:15633126-Liver Neoplasms,
pubmed-meshheading:15633126-Neoplasm Recurrence, Local,
pubmed-meshheading:15633126-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:15633126-Protein-Tyrosine Kinases,
pubmed-meshheading:15633126-Receptor, Fibroblast Growth Factor, Type 3,
pubmed-meshheading:15633126-Receptors, Fibroblast Growth Factor,
pubmed-meshheading:15633126-Signal Transduction,
pubmed-meshheading:15633126-Tretinoin,
pubmed-meshheading:15633126-rho GTP-Binding Proteins
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pubmed:year |
2005
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pubmed:articleTitle |
Acyclic retinoid inhibits human hepatoma cell growth by suppressing fibroblast growth factor-mediated signaling pathways.
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pubmed:affiliation |
Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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