rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2005-4-11
|
pubmed:abstractText |
The beta-adrenoceptor (beta-AR) plays an important role in heart failure. Recently, the new tracer (S)-[11C]CGP12388 has been developed. It displays excellent properties for investigation of the cardiac beta-ARs in vivo with positron emission tomography (PET). Furthermore, the simple production method allows its use in a routine clinical setting. The aim of this study was to investigate whether decreased myocardial beta-AR density in patients with idiopathic dilated cardiomyopathy (IDC) can be estimated using (S)-[11C]CGP12388 PET.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1619-7070
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
443-7
|
pubmed:meshHeading |
pubmed-meshheading:15592928-Adult,
pubmed-meshheading:15592928-Aged,
pubmed-meshheading:15592928-Benzimidazoles,
pubmed-meshheading:15592928-Carbon Radioisotopes,
pubmed-meshheading:15592928-Cardiomyopathy, Dilated,
pubmed-meshheading:15592928-Down-Regulation,
pubmed-meshheading:15592928-Female,
pubmed-meshheading:15592928-Heart,
pubmed-meshheading:15592928-Humans,
pubmed-meshheading:15592928-Ligands,
pubmed-meshheading:15592928-Male,
pubmed-meshheading:15592928-Middle Aged,
pubmed-meshheading:15592928-Myocardium,
pubmed-meshheading:15592928-Positron-Emission Tomography,
pubmed-meshheading:15592928-Radiopharmaceuticals,
pubmed-meshheading:15592928-Receptors, Adrenergic, beta,
pubmed-meshheading:15592928-Tissue Distribution
|
pubmed:year |
2005
|
pubmed:articleTitle |
Myocardial beta-adrenoceptor downregulation in idiopathic dilated cardiomyopathy measured in vivo with PET using the new radioligand (S)-[11C]CGP12388.
|
pubmed:affiliation |
Deparment of Cardiology, Groningen University Hospital, Groningen, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|