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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1992-5-5
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pubmed:abstractText |
Urokinase-type plasminogen activator (u-PA) is thought to be implicated in cancer invasion and metastasis. The aim of this study was to determine whether the u-PA content of cancer tissue is a prognostic factor in bladder cancer. Tissue samples from 46 patients with bladder cancer were assessed for u-PA antigen by a highly sensitive enzyme immunoassay. The relationships between the u-PA level in extracts of bladder cancer and the survival rates of the bladder-cancer patients were examined. Patients with a high u-PA level (8 ng/mg of protein and more) showed a statistically significantly higher rate of survival than those with a low u-PA level (p less than 0.005). The u-PA antigen level in cancer tissue was significantly lower in low-graded and non-invasive cancers than in others (p less than 0.01).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0020-7136
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
871-3
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1555885-Aged,
pubmed-meshheading:1555885-Biopsy,
pubmed-meshheading:1555885-Follow-Up Studies,
pubmed-meshheading:1555885-Humans,
pubmed-meshheading:1555885-Immunoenzyme Techniques,
pubmed-meshheading:1555885-Immunoglobulin G,
pubmed-meshheading:1555885-Probability,
pubmed-meshheading:1555885-Prognosis,
pubmed-meshheading:1555885-Reference Values,
pubmed-meshheading:1555885-Time Factors,
pubmed-meshheading:1555885-Tumor Markers, Biological,
pubmed-meshheading:1555885-Urinary Bladder Neoplasms,
pubmed-meshheading:1555885-Urokinase-Type Plasminogen Activator
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pubmed:year |
1992
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pubmed:articleTitle |
The content of urokinase-type plasminogen activator antigen as a prognostic factor in urinary bladder cancer.
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pubmed:affiliation |
Department of Urology, Miyazaki Medical College, Japan.
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pubmed:publicationType |
Journal Article
|