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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2004-11-19
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pubmed:abstractText |
The risk for Crohn's disease (CD) is determined in part by genetic factors. Three recently described mutations in the CARD15(NOD2) gene have been associated with adult-onset CD. We investigated the effect of CARD15 mutations on disease manifestation, disease progression, and the risk for early surgery in childhood-onset CD.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1542-3565
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1003-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15551253-Adolescent,
pubmed-meshheading:15551253-Child,
pubmed-meshheading:15551253-Child, Preschool,
pubmed-meshheading:15551253-Crohn Disease,
pubmed-meshheading:15551253-Disease Progression,
pubmed-meshheading:15551253-Endoscopy, Gastrointestinal,
pubmed-meshheading:15551253-Female,
pubmed-meshheading:15551253-Genetic Predisposition to Disease,
pubmed-meshheading:15551253-Genetic Variation,
pubmed-meshheading:15551253-Genotype,
pubmed-meshheading:15551253-Humans,
pubmed-meshheading:15551253-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:15551253-Logistic Models,
pubmed-meshheading:15551253-Male,
pubmed-meshheading:15551253-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:15551253-Phenotype,
pubmed-meshheading:15551253-Proportional Hazards Models
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pubmed:year |
2004
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pubmed:articleTitle |
CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn's disease.
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pubmed:affiliation |
Department of Pediatrics, Medical College of Wisconsin, Milwaukee 53226, USA. skuga@mcw.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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