Source:http://linkedlifedata.com/resource/pubmed/id/15526799
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2004-11-5
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pubmed:abstractText |
In 1983, a male lamb exhibiting a pronounced muscular hypertrophy, particularly noticeable in the hind quarters, was born into a commercial Dorset flock in Oklahoma. The ram was premonitorily called Solid Gold. He subsequently produced offspring expressing the unusual phenotype, which is referred to as callipyge (Greek: calli- beautiful + -pyge buttocks). Animals demonstrating the callipyge phenotype are all descendants of this founder ram. These animals produce leaner, higher yielding carcasses, but there is some concern with decreased tenderness of the loin. Genetic characterization of the locus has demonstrated a unique mode of inheritance termed polar overdominance, in which only heterozygous offspring inheriting the mutation from their sire express the phenotype. The three other genotypes are normal in appearance. Progeny data indicate that reactivation of the maternal callipyge allele occurs after passage through the male germ line, although this reactivation is not absolute. The callipyge gene has been mapped to the distal end of ovine chromosome 18.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0021-8812
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
77 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
221-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15526799-Animals,
pubmed-meshheading:15526799-Crosses, Genetic,
pubmed-meshheading:15526799-Female,
pubmed-meshheading:15526799-Heterozygote,
pubmed-meshheading:15526799-Male,
pubmed-meshheading:15526799-Muscle, Skeletal,
pubmed-meshheading:15526799-Mutation,
pubmed-meshheading:15526799-Phenotype,
pubmed-meshheading:15526799-Sheep
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pubmed:year |
1999
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pubmed:articleTitle |
The callipyge phenomenon: evidence for unusual genetic inheritance.
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pubmed:affiliation |
Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan 84322-4700, USA. fanoelle@cc.usu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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