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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-10-29
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pubmed:abstractText |
Activated factor VIIa (FVIIa) was developed to treat hemophiliacs with high-titer antibodies to factor VIII. FVIIa initiates thrombin formation by binding with exposed tissue factor. Anecdotal reports have described the utility of FVIIa in correcting coagulopathy from trauma, but no large series exists. We present our experience with 81 coagulopathic trauma patients treated using FVIIa in years 2001-2003, compared with "control" patients matched from the trauma registry from the same time period.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-5282
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
709-18; discussion 718-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15514523-Adolescent,
pubmed-meshheading:15514523-Aged,
pubmed-meshheading:15514523-Aged, 80 and over,
pubmed-meshheading:15514523-Blood Coagulation Disorders,
pubmed-meshheading:15514523-Case-Control Studies,
pubmed-meshheading:15514523-Cause of Death,
pubmed-meshheading:15514523-Comorbidity,
pubmed-meshheading:15514523-Dose-Response Relationship, Drug,
pubmed-meshheading:15514523-Drug Administration Schedule,
pubmed-meshheading:15514523-Factor VIIa,
pubmed-meshheading:15514523-Female,
pubmed-meshheading:15514523-Follow-Up Studies,
pubmed-meshheading:15514523-Hemorrhage,
pubmed-meshheading:15514523-Humans,
pubmed-meshheading:15514523-Male,
pubmed-meshheading:15514523-Middle Aged,
pubmed-meshheading:15514523-Multiple Trauma,
pubmed-meshheading:15514523-Probability,
pubmed-meshheading:15514523-Reference Values,
pubmed-meshheading:15514523-Retrospective Studies,
pubmed-meshheading:15514523-Risk Assessment,
pubmed-meshheading:15514523-Survival Analysis,
pubmed-meshheading:15514523-Trauma Centers,
pubmed-meshheading:15514523-Treatment Outcome,
pubmed-meshheading:15514523-Wounds and Injuries
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pubmed:year |
2004
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pubmed:articleTitle |
Factor VIIa for correction of traumatic coagulopathy.
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pubmed:affiliation |
Program in Trauma, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. rdutton@umaryland.edu
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pubmed:publicationType |
Journal Article,
Comparative Study
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