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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-9-7
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pubmed:abstractText |
Comparative genomic hybridization (CGH) is a powerful method to investigate chromosomal imbalances in tumor cells. However, DNA quantity and quality can be limiting factors for successful CGH analysis. The aim of this study was to investigate the applicability of degenerate oligonucleotide-primed PCR (DOP-PCR) and a recently developed linker-adapter-mediated PCR (LA-PCR) for whole genome amplification for use in CGH, especially for difficult source material.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1552-4922
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pubmed:author |
pubmed-author:AubeleMichaelaM,
pubmed-author:BergerWalterW,
pubmed-author:ElblingLeonillaL,
pubmed-author:Grasl-KrauppBettinaB,
pubmed-author:HolzmannKlausK,
pubmed-author:MarosiChristineC,
pubmed-author:MickscheMichaelM,
pubmed-author:PirkerChristineC,
pubmed-author:RaidlMariaM,
pubmed-author:Spiegl-KreineckerSabineS,
pubmed-author:SteinerElisabethE
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pubmed:copyrightInfo |
Copyright 2004 Wiley-Liss, Inc
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
26-34
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pubmed:dateRevised |
2007-7-24
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pubmed:meshHeading |
pubmed-meshheading:15351986-Cell Line, Tumor,
pubmed-meshheading:15351986-Chromosome Aberrations,
pubmed-meshheading:15351986-DNA, Neoplasm,
pubmed-meshheading:15351986-Genome,
pubmed-meshheading:15351986-Humans,
pubmed-meshheading:15351986-In Situ Hybridization, Fluorescence,
pubmed-meshheading:15351986-Nucleic Acid Amplification Techniques,
pubmed-meshheading:15351986-Nucleic Acid Hybridization,
pubmed-meshheading:15351986-Polymerase Chain Reaction
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pubmed:year |
2004
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pubmed:articleTitle |
Whole genome amplification for CGH analysis: Linker-adapter PCR as the method of choice for difficult and limited samples.
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pubmed:affiliation |
Division of Applied & Experimental Oncology, Institute of Cancer Research, Vienna University, Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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