Linked Life Data

15308207

Source:http://linkedlifedata.com/resource/pubmed/id/15308207

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2004-8-13
pubmed:abstractText
Recent data have revealed that the mitotic spindle might form by centrosome-independent mechanisms, even in centrosome-containing cells. This suggests that spindle assembly might proceed by a generally conserved acentrosomal mechanism in all higher eukaryotes, regardless of the presence of centrosomes. Thus, what is the role of centrosomes in mitosis? We propose that these organelles are needed to generate radial arrays of microtubules that integrate preassembled (by centrosome-independent mechanisms) spindle components into a common spindle and orientate the spindle within malleable animal cells.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0962-8924
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
413-9
pubmed:dateRevised
2011-3-1
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
E pluribus unum: towards a universal mechanism for spindle assembly.
pubmed:affiliation
Morrill Science Center, Department of Biology, University of Massachusetts, Amherst, MA 01003, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review