Source:http://linkedlifedata.com/resource/pubmed/id/15304013
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2004-8-12
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pubmed:databankReference | |
pubmed:abstractText |
Two new HLA-DRB1 alleles have been found by using high-resolution sequence-based typing. The two sequences have been officially named DRB1*1350 (HWS10001327-AY048687) and DRB1*140502 (HWS10001790-AY129430). DRB1*1350 differs from DRB1*110101 by two amino acids at positions 37 (Y-->N) and 58 (A-->E). This allele may arise from gene conversion between DRB1*110101 and DRB1*130201 or DRB1*030101, which are commonly found in Taiwan populations. The other allele, DRB1*140502, obtained from a patient with rheumatoid arthritis, differs from DRB1*140501 at codon 58 (GCC-->GCT). However, it causes no change in amino acid sequence and would therefore not have direct clinical implications.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0001-2815
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
300-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15304013-Alleles,
pubmed-meshheading:15304013-Amino Acid Sequence,
pubmed-meshheading:15304013-Asian Continental Ancestry Group,
pubmed-meshheading:15304013-Base Sequence,
pubmed-meshheading:15304013-Female,
pubmed-meshheading:15304013-HLA-DR Antigens,
pubmed-meshheading:15304013-HLA-DRB1 Chains,
pubmed-meshheading:15304013-Humans,
pubmed-meshheading:15304013-Male,
pubmed-meshheading:15304013-Molecular Sequence Data,
pubmed-meshheading:15304013-Taiwan
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pubmed:year |
2004
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pubmed:articleTitle |
Identification of two new HLA-DRB1 alleles: HLA-DRB1*1350 and DRB1*140502.
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pubmed:affiliation |
Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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