| pubmed-article:1528855 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1528855 | lifeskim:mentions | umls-concept:C0028959 | lld:lifeskim |
| pubmed-article:1528855 | lifeskim:mentions | umls-concept:C0765250 | lld:lifeskim |
| pubmed-article:1528855 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:1528855 | pubmed:issue | 18 | lld:pubmed |
| pubmed-article:1528855 | pubmed:dateCreated | 1992-10-22 | lld:pubmed |
| pubmed-article:1528855 | pubmed:abstractText | alpha-L-Fucosidase (alpha-L-fucoside fucohydrolase; EC 3.2.1.51) preparations from Streptomyces sp. 142 were found to contain an enzyme specific for lacto-N-biosidic (Gal beta 1-3GlcNAc beta 1-) linkages (type 1 structure) in oligosaccharides. The enzyme preparation, which was eluted after alpha-fucosidase from a CM-Sepharose column, contained some alpha-fucosidase activity but was free from other glycosidases and proteases. Substrate specificity studies with oligosaccharides labeled with 2-aminopyridine showed that the enzyme specifically hydrolyzed lacto-N-tetraose (Gal beta 1-3GlcNAc beta 1-3Gal beta 1-4Glc) but did not hydrolyze lacto-N-neotetraose (Gal beta 1-4GlcNAc beta 1-3Gal beta 1-4Glc), lacto-N-triose, sialyl lacto-N-tetraose, lacto-N-fucopentaose I, II, or III, asialo-GM1 tetrasaccharide, or poly-N-acetyllactosamine. Structural analysis of the enzyme digest of the N-acetyllactosamine type of triantennary sugar chain with type 1 structure showed that lacto-N-biose (Gal beta 1-3GlcNAc) and the N-acetyllactosamine type of biantennary sugar chain were produced. Thus this enzyme was tentatively named lacto-N-biosidase, because it hydrolyzes oligosaccharides containing a type 1 structure at the nonreducing terminus and produces lacto-N-biose. | lld:pubmed |
| pubmed-article:1528855 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1528855 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1528855 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1528855 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1528855 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1528855 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1528855 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1528855 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1528855 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1528855 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1528855 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:1528855 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:1528855 | pubmed:author | pubmed-author:SanoMM | lld:pubmed |
| pubmed-article:1528855 | pubmed:author | pubmed-author:HayakawaKK | lld:pubmed |
| pubmed-article:1528855 | pubmed:author | pubmed-author:KatzDD | lld:pubmed |
| pubmed-article:1528855 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1528855 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:1528855 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:1528855 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1528855 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1528855 | pubmed:pagination | 8512-6 | lld:pubmed |
| pubmed-article:1528855 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:meshHeading | pubmed-meshheading:1528855-... | lld:pubmed |
| pubmed-article:1528855 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1528855 | pubmed:articleTitle | An enzyme releasing lacto-N-biose from oligosaccharides. | lld:pubmed |
| pubmed-article:1528855 | pubmed:affiliation | Biotechnology Research Laboratories, Takara Shuzo Co., Ltd., Shiga, Japan. | lld:pubmed |
| pubmed-article:1528855 | pubmed:publicationType | Journal Article | lld:pubmed |
