Linked Life Data

15217941

Source:http://linkedlifedata.com/resource/pubmed/id/15217941

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12 Pt 1
pubmed:dateCreated
2004-6-25
pubmed:abstractText
The purpose is to determine the effect of food on the bioavailability of S-1, an oral formulation of the 5-fluorouracil (5FU) prodrug Ftorafur (FT), 5-chloro-2,4-dihydroxypyridine (CDHP), a dihydropyrimidine dehydrogenase inhibitor, and oxonic acid (an inhibitor of 5FU phosphoribosylation in normal gut mucosa) in a molar ratio of 1:0.4:1.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4072-6
pubmed:dateRevised
2006-9-18
pubmed:meshHeading
pubmed-meshheading:15217941-Administration, Oral, pubmed-meshheading:15217941-Adult, pubmed-meshheading:15217941-Aged, pubmed-meshheading:15217941-Antimetabolites, Antineoplastic, pubmed-meshheading:15217941-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:15217941-Area Under Curve, pubmed-meshheading:15217941-Biological Availability, pubmed-meshheading:15217941-Cross-Over Studies, pubmed-meshheading:15217941-Eating, pubmed-meshheading:15217941-Female, pubmed-meshheading:15217941-Fluorouracil, pubmed-meshheading:15217941-Food, pubmed-meshheading:15217941-Humans, pubmed-meshheading:15217941-Kinetics, pubmed-meshheading:15217941-Male, pubmed-meshheading:15217941-Middle Aged, pubmed-meshheading:15217941-Neoplasms, pubmed-meshheading:15217941-Oxonic Acid, pubmed-meshheading:15217941-Phosphorylation, pubmed-meshheading:15217941-Pyridines, pubmed-meshheading:15217941-Tegafur, pubmed-meshheading:15217941-Time Factors
pubmed:year
2004
pubmed:articleTitle
The effect of food on the pharmacokinetics of S-1 after single oral administration to patients with solid tumors.
pubmed:affiliation
Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands. gjpeters@vumc.nl
pubmed:publicationType
Journal Article, Clinical Trial, Controlled Clinical Trial