Source:http://linkedlifedata.com/resource/pubmed/id/15159505
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2004-5-25
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pubmed:abstractText |
A woman aged 59 years with adult-onset progressive myopathy had anti-Golgi (giantin) autoantibody in the serum. Limb-muscle biopsy revealed chronic myopathy with paucity of cellular reactions and reduced immunostaining for alpha-dystroglycan. The similarity of the current patient with cases of hereditary alpha-dystroglycanopathies (Fukuyama-type congenital muscular dystrophy, Walker-Warburg syndrome, muscle-eye-brain disease, congenital muscular dystrophy type 1C, and limb-girdle muscular dystrophy type 2I) suggests that the Golgi apparatus is the target organelle in a subset of myopathies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1526-632X
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
25
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1891-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15159505-Antibody Specificity,
pubmed-meshheading:15159505-Autoantibodies,
pubmed-meshheading:15159505-Autoantigens,
pubmed-meshheading:15159505-Autoimmune Diseases,
pubmed-meshheading:15159505-Disease Progression,
pubmed-meshheading:15159505-Female,
pubmed-meshheading:15159505-Golgi Apparatus,
pubmed-meshheading:15159505-Humans,
pubmed-meshheading:15159505-Middle Aged,
pubmed-meshheading:15159505-Muscle, Skeletal,
pubmed-meshheading:15159505-Muscular Disorders, Atrophic,
pubmed-meshheading:15159505-Ribonucleases
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pubmed:year |
2004
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pubmed:articleTitle |
Progressive myopathy with circulating autoantibody against giantin in the Golgi apparatus.
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pubmed:affiliation |
Department of Neurology, Aichi Medical University, Japan. sahashi@amugw.aichi-med-u.ac.jp
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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