Source:http://linkedlifedata.com/resource/pubmed/id/15153682
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-5-21
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pubmed:abstractText |
The non-radioisotopic modification of murine local lymph node assay (LLNA) by using 5-bromo-2'-deoxyuridine (BrdU) was conducted to investigate the strain-related difference of the responsiveness of mice to p-benzoquinone (PBQ) with BALB/cAnN, CBA/JN and CD-1 mouse strains. Strain and dose related differences were analyzed by two-way analysis of variance (two-way ANOVA). CBA/JN was considered to be the highest responsive strain to PBQ, and interaction was detected between CD-1 and each of the other inbred strains. These results support the recommendation in the OECD test guideline 429 and the skin sensitization test guideline of US-EPA with regard to the selection of mouse strain for LLNA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1341-1357
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
171-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15153682-Analysis of Variance,
pubmed-meshheading:15153682-Animals,
pubmed-meshheading:15153682-Benzoquinones,
pubmed-meshheading:15153682-Bromodeoxyuridine,
pubmed-meshheading:15153682-Dose-Response Relationship, Drug,
pubmed-meshheading:15153682-Local Lymph Node Assay,
pubmed-meshheading:15153682-Lymph Nodes,
pubmed-meshheading:15153682-Mice,
pubmed-meshheading:15153682-Mice, Inbred Strains
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pubmed:year |
2004
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pubmed:articleTitle |
Differences in responsiveness of mouse strain against p-benzoquinone as assessed by non-radioisotopic murine local lymph node assay.
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pubmed:affiliation |
Hita Laboratory, Chemicals Evaluation and Research Institute, Japan, Oita, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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