rdf:type |
|
lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0027051,
umls-concept:C0034693,
umls-concept:C0037570,
umls-concept:C0078836,
umls-concept:C0332161,
umls-concept:C0332281,
umls-concept:C0333959,
umls-concept:C0443288,
umls-concept:C0871261,
umls-concept:C1522565,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1958507,
umls-concept:C2911692
|
pubmed:issue |
1
|
pubmed:dateCreated |
2004-5-11
|
pubmed:abstractText |
In patients with myocardial infarction (MI)-induced heart failure, angiotensin-converting enzyme (ACE) inhibitors are proven effective therapy in inhibiting the progression towards overt heart failure. However, the prognosis in these patients is still very poor, and optimisation of therapy is warranted. The antihypertensive and renoprotective effects of ACE inhibitors (ACE-Is) can be substantially enhanced by dietary sodium restriction. In line with the latter, the aim of the present study was to explore whether dietary sodium restriction enhances the efficacy of ACE-I after MI.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1470-3203
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
27-32
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15136971-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:15136971-Animals,
pubmed-meshheading:15136971-Blood Pressure,
pubmed-meshheading:15136971-Captopril,
pubmed-meshheading:15136971-Diet, Sodium-Restricted,
pubmed-meshheading:15136971-Heart Ventricles,
pubmed-meshheading:15136971-Hypertrophy, Left Ventricular,
pubmed-meshheading:15136971-Kidney,
pubmed-meshheading:15136971-Male,
pubmed-meshheading:15136971-Myocardial Infarction,
pubmed-meshheading:15136971-Myocardium,
pubmed-meshheading:15136971-Organ Size,
pubmed-meshheading:15136971-Peptidyl-Dipeptidase A,
pubmed-meshheading:15136971-Rats,
pubmed-meshheading:15136971-Rats, Wistar,
pubmed-meshheading:15136971-Ventricular Function, Left
|
pubmed:year |
2004
|
pubmed:articleTitle |
Dietary sodium restriction specifically potentiates left ventricular ACE inhibition by zofenopril, and is associated with attenuated hypertrophic response in rats with myocardial infarction.
|
pubmed:affiliation |
Department of Clinical Pharmacology, University of Groningen, Groningen, The Netherlands. b.westendorp@med.rug.nl
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|