Source:http://linkedlifedata.com/resource/pubmed/id/15110205
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
2004-4-27
|
| pubmed:abstractText |
B-type natriuretic peptide (BNP) and early diastolic transmitral velocity/tissue Doppler mitral annular velocity (E/Ea) both estimate left ventricular filling pressure, but have not been compared in the diagnosis of congestive heart failure (CHF). One hundred twenty-two hospital inpatients with suspected CHF underwent simultaneous clinical examination, BNP measurement, and comprehensive echo-Doppler examination. The accuracy of BNP and echocardiography was compared with the Framingham criteria diagnosis of CHF. Seventy patients (57%) had clinical CHF, whereas 52 (43%) did not. In all patients, the optimal BNP cutoff was >250 pg/ml (sensitivity 86%, specificity 77%). E/Ea >15 had 83% sensitivity and 82% specificity, whereas comprehensive echo-Doppler had 95% sensitivity and 88% specificity for CHF. In patients with normal ejection fraction, the optimal BNP cutoff was >150 pg/ml (sensitivity 79%, specificity 85%). E/Ea >15 had 79% sensitivity and 93% specificity, whereas comprehensive echo-Doppler had 85% sensitivity and 96% specificity for CHF. In patients with reduced ejection fraction, the optimal BNP cutoff was >300 pg/ml (sensitivity 88%, specificity 60%). E/Ea >15 had 92% sensitivity and 72% specificity, whereas comprehensive echo-Doppler had 96% sensitivity and 80% specificity (p = 0.08 compared with BNP) for CHF. Overall, BNP and E/Ea have similar diagnostic accuracy for CHF in this patient population. In patients with reduced ejection fraction, comprehensive echo-Doppler trended toward higher specificity than BNP for clinical CHF.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0002-9149
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
93
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1130-5
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:15110205-Adult,
pubmed-meshheading:15110205-Aged,
pubmed-meshheading:15110205-Biological Markers,
pubmed-meshheading:15110205-Blood Flow Velocity,
pubmed-meshheading:15110205-Echocardiography, Doppler,
pubmed-meshheading:15110205-Female,
pubmed-meshheading:15110205-Heart Atria,
pubmed-meshheading:15110205-Heart Failure,
pubmed-meshheading:15110205-Humans,
pubmed-meshheading:15110205-Male,
pubmed-meshheading:15110205-Middle Aged,
pubmed-meshheading:15110205-Mitral Valve Insufficiency,
pubmed-meshheading:15110205-Natriuretic Peptide, Brain,
pubmed-meshheading:15110205-Predictive Value of Tests,
pubmed-meshheading:15110205-Sensitivity and Specificity,
pubmed-meshheading:15110205-Stroke Volume,
pubmed-meshheading:15110205-Texas,
pubmed-meshheading:15110205-Ventricular Pressure
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
Comparative accuracy of B-type natriuretic peptide and tissue Doppler echocardiography in the diagnosis of congestive heart failure.
|
| pubmed:affiliation |
Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, Texas, USA. hishamd@bcm.tmc.edu
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies
|