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pubmed-article:15077293pubmed:abstractTextIn the era of postgenomic research, linkage- and association-based strategies are beginning to reveal novel complex disease genes. Using such an approach, a functional haplotype of the peptidylarginine deiminase 4 gene (PADI4) has recently been identified as a gene conferring susceptibility to rheumatoid arthritis (RA) in a Japanese population. In the present study, we investigated the association of single-nucleotide polymorphisms (SNPs) in the PADI4 gene with RA in a UK population.lld:pubmed
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pubmed-article:15077293pubmed:articleTitleA functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population.lld:pubmed
pubmed-article:15077293pubmed:affiliationUniversity of Manchester, Manchester, UK. ABarton@fs1.ser.man.ac.uklld:pubmed
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