pubmed:abstractText |
Thrombin, a central enzyme in the clotting cascade, plays a role not only in thrombosis but also in the progression of atherosclerosis. We studied the relationship between prothrombin fragment 1+2 (F1+2), a specific marker of thrombin generation in vivo, and carotid intima-media thickness (IMT), an index of subclinical atherosclerosis.
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pubmed:affiliation |
Atherosclerosis Research, University Clinic, School of Medicine, University of Navarra, Pamplona, Spain. japaramo@unav.es
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