Linked Life Data

14963917

Source:http://linkedlifedata.com/resource/pubmed/id/14963917

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2004-2-13
pubmed:abstractText
The associations of the Bsm1 polymorphism of vitamin D receptor gene and blood lead, zinc protoporphyrin and physical development in 476 environmental lead-exposed children were studied. After blood lead level, age, sex and education level of the patients were adjusted by analysis of covariance, the children with B allele had larger head circumference than those with bb genotype(P = 0.02). While the subjects were stratified by blood lead level and sex, the statistically significant difference in head circumference between different Bsm1 genotypes was found only in high-blood-lead subgroup and in male subgroup. No significant influence of Bsm1 polymorphism on blood lead level, zinc protoporphyrin, height and weight was found, suggesting that the Bsm1 polymorphism of VDR gene may modify the effect of lead on the skull development of children highly exposed to lead.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1000-8020
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
610-2
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Associations of Bsm1 polymorphism of the vitamin D receptor gene and blood lead, zinc protoporphyrin, and physical development in 476 environmental lead-exposed children].
pubmed:affiliation
National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't