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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1993-2-24
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pubmed:abstractText |
To understand better the organization and linkage of the interleukin genes, IL4 and IL5, we prepared long-range restriction maps of five yeast artificial chromosomes (YACs) containing IL5. We determined that IL4 and IL5 are within 100-170 kb, and that the regions surrounding these genes contain several GC-rich areas. Fluorescence in situ chromosomal analysis demonstrated that three of the five YAC clones contain non-contiguous genomic sequences originating from multiple human chromosomes.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0301-0171
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
263-5
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:1486800-Base Sequence,
pubmed-meshheading:1486800-Chromosome Mapping,
pubmed-meshheading:1486800-Chromosomes, Fungal,
pubmed-meshheading:1486800-Chromosomes, Human, Pair 5,
pubmed-meshheading:1486800-DNA, Single-Stranded,
pubmed-meshheading:1486800-Electrophoresis, Gel, Pulsed-Field,
pubmed-meshheading:1486800-Genetic Linkage,
pubmed-meshheading:1486800-Genome, Human,
pubmed-meshheading:1486800-Genomic Library,
pubmed-meshheading:1486800-Humans,
pubmed-meshheading:1486800-In Situ Hybridization, Fluorescence,
pubmed-meshheading:1486800-Interleukin-4,
pubmed-meshheading:1486800-Interleukin-5,
pubmed-meshheading:1486800-Molecular Sequence Data,
pubmed-meshheading:1486800-Polymerase Chain Reaction,
pubmed-meshheading:1486800-Restriction Mapping
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pubmed:year |
1992
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pubmed:articleTitle |
Characterization of yeast artificial chromosomes containing interleukin genes on human chromosome 5.
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pubmed:affiliation |
Department of Medicine, University of Chicago, IL 60637.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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