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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1993-2-18
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pubmed:abstractText |
Anticardiolipin antibodies of the IgG, IgM and IgA isotypes and soluble IL-6 were measured in paired serum and cerebrospinal fluid samples from five patients with neuro-Behçet's syndrome. Another five patients with non-inflammatory neurological diseases were also studied as a control group. Anticardiolipin antibodies, especially the IgM isotype, and IL-6 were highly elevated in the cerebrospinal fluid of patients with neuro-Behçet's. Levels of both IgM isotype anticardiolipin antibodies and IL-6 in the cerebrospinal fluid dropped after disease activity subsided. These results suggest that the increase in IgM isotype anticardiolipin antibodies and IL-6 in cerebrospinal fluid may be involved in the immune response of neuro-Behçet's within the central nervous system. Serial measurements of IgM isotype anticardiolipin antibodies and IL-6 in the cerebrospinal fluid may be useful in evaluating disease activity in neuro-Behçet's.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Anticardiolipin,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin A,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin M,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6
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pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
599-602
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1483312-Adult,
pubmed-meshheading:1483312-Antibodies, Anticardiolipin,
pubmed-meshheading:1483312-Asian Continental Ancestry Group,
pubmed-meshheading:1483312-Behcet Syndrome,
pubmed-meshheading:1483312-China,
pubmed-meshheading:1483312-Female,
pubmed-meshheading:1483312-Humans,
pubmed-meshheading:1483312-Immunoglobulin A,
pubmed-meshheading:1483312-Immunoglobulin G,
pubmed-meshheading:1483312-Immunoglobulin M,
pubmed-meshheading:1483312-Interleukin-6,
pubmed-meshheading:1483312-Male,
pubmed-meshheading:1483312-Middle Aged,
pubmed-meshheading:1483312-Nervous System Diseases
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pubmed:articleTitle |
Anticardiolipin antibodies and interleukin-6 in cerebrospinal fluid and blood of Chinese patients with neuro-Behçet's syndrome.
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pubmed:affiliation |
Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, R.O.C.
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pubmed:publicationType |
Journal Article
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