Source:http://linkedlifedata.com/resource/pubmed/id/14764544
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
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| pubmed:dateCreated |
2004-4-30
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| pubmed:abstractText |
A comprehensive gene expression database is essential for computer modeling and simulation of biological phenomena, including development. Development is a four-dimensional (4D; 3D structure and time course) phenomenon. We are constructing a 4D database of gene expression for the early embryogenesis of the nematode Caenorhabditis elegans. As a framework of the 4D database, we have constructed computer graphics (CG), into which we will incorporate the expression data of a number of genes at the subcellular level. However, the assignment of 3D distribution of gene products (protein, mRNA), of embryos at various developmental stages, is both difficult and tedious. We need to automate this process. For this purpose, we developed a new system, named SPI after superimposing fluorescent confocal microscopic data onto a CG framework.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
1367-4803
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1097-109
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:14764544-Animals,
pubmed-meshheading:14764544-Caenorhabditis elegans,
pubmed-meshheading:14764544-Caenorhabditis elegans Proteins,
pubmed-meshheading:14764544-Database Management Systems,
pubmed-meshheading:14764544-Databases, Factual,
pubmed-meshheading:14764544-Embryonic and Fetal Development,
pubmed-meshheading:14764544-Gene Expression Profiling,
pubmed-meshheading:14764544-Image Interpretation, Computer-Assisted,
pubmed-meshheading:14764544-Information Storage and Retrieval,
pubmed-meshheading:14764544-Microscopy, Confocal,
pubmed-meshheading:14764544-Models, Biological,
pubmed-meshheading:14764544-Reproducibility of Results,
pubmed-meshheading:14764544-Sensitivity and Specificity,
pubmed-meshheading:14764544-Software,
pubmed-meshheading:14764544-Subcellular Fractions,
pubmed-meshheading:14764544-Tissue Distribution,
pubmed-meshheading:14764544-User-Computer Interface
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
SPI: a tool for incorporating gene expression data into a four-dimensional database of Caenorhabditis elegans embryogenesis.
|
| pubmed:affiliation |
Genome Biology Laboratory, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan.
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Validation Studies
|