Source:http://linkedlifedata.com/resource/pubmed/id/14698166
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2003-12-30
|
pubmed:abstractText |
A series of 7-(substituted)aminomethyl quinolones was synthesized and evaluated for antibacterial activity. Derivatives with (monoalkyl)aminomethyl substituent at C-7 displayed high in vitro activities comparable to Lomefloxacin against gram-negative organisms, whereas those bearing a [(substituted)phenyl]aminomethyl side chain at C-7 demonstrated good activities against gram-positive organisms as potent as Lomefloxacin and Vancomycin.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0960-894X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
19
|
pubmed:volume |
14
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
393-5
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14698166-Anti-Bacterial Agents,
pubmed-meshheading:14698166-Drug Resistance, Microbial,
pubmed-meshheading:14698166-Gram-Negative Bacteria,
pubmed-meshheading:14698166-Gram-Positive Bacteria,
pubmed-meshheading:14698166-Microbial Sensitivity Tests,
pubmed-meshheading:14698166-Quinolones
|
pubmed:year |
2004
|
pubmed:articleTitle |
Synthesis and antibacterial activity of 7-(substituted)aminomethyl quinolones.
|
pubmed:affiliation |
Biomolecular Structure Center, Department of Biochemistry, Box 357350, University of Washington, Seattle, WA 98195, USA. zhenfa@u.washington.edu
|
pubmed:publicationType |
Journal Article,
Comparative Study
|